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what is urea made up of?

Urea is a widely used compound, but have you ever wondered what the interior of this seemingly simple white crystal is composed of?

To truly understand urea, we need to delve into its chemical formula, molecular structure, and how it is manufactured on three levels.

what is urea made up of

urea Chemical composition

The chemical formula for urea is simple: (NH₂)₂CO

Carbon (C): A single carbon atom forms the backbone of a molecule. 

Oxygen (O): One oxygen atom forms a carbonyl group (C=O) with a carbon double bond. 

Nitrogen (N): Two nitrogen atoms, each of which combines with two hydrogen atoms to form an amino group (-NH₂) 

Hydrogen (H): Four hydrogen atoms, two of which are attached to each nitrogen atom in the amino group. 

In short, urea is a simple organic molecule composed of four basic elements: carbon, oxygen, nitrogen, and hydrogen.

Urea Molecular Structure

The chemical formula only tells us ‘what is there’, while the molecular structure shows us how these atoms are arranged and connected, which determines the unique properties of urea.

The structure of urea can be described as follows:

A carbon atom (C) is located at the center.
This carbon atom forms a double bond with an oxygen atom (O) (written as C=O). This C=O structure is chemically referred to as the “Carbonyl Group”.

At the same time, this central carbon atom also forms single bonds with two amino groups (-NH₂). Each amino group is composed of one nitrogen atom and two hydrogen atoms.

So, you can imagine a central carbon atom, like outstretched hands, one hand (double bond) tightly gripping an oxygen atom, and the other two hands (single bond) each gripping an amino (-NH₂) group.

Why is this structure important?

This structure endows urea with a high nitrogen content (about 46%), making it an efficient nitrogen fertilizer. Meanwhile, the carbonyl and amino groups in the molecule give it polarity and enable it to form strong hydrogen bonds with water, which is also why urea is highly soluble in water.

Natural urea and synthetic urea: how they are formed

Urea has the same chemical composition in natural and synthetic forms.  

Natural urea

In nature, urea is produced by the liver of mammals (including humans) as waste from protein metabolism. When we eat protein-rich foods (meat, eggs, beans), our body breaks down protein into amino acids. The excess nitrogen in these amino acids is converted into urea and then excreted through urine.

Synthetic urea: industrial production

The raw materials for synthesizing urea are simple: ammonia (NH3) and carbon dioxide (CO2).

This process is carried out in two steps under high pressure and high temperature:

  • Step 1: Ammonia and carbon dioxide react to produce an unstable intermediate – ammonium carbamate.
  • Step 2: Heat ammonium carbamate to dehydrate it, forming urea and water.

Ammonia used in industry is mainly produced through the Haber Bosch process using natural gas and nitrogen from the air. At the same time, carbon dioxide is typically a byproduct of other industrial processes.

Why is the composition of urea important for its use

The chemical composition of urea directly realizes its diverse applications:

High nitrogen content: Urea has a nitrogen content of 46%, making it an ideal choice for fertilizers. Plants absorb nitrogen from urea (after soil bacteria convert it into ammonium nitrogen), providing fuel for growth, leaf development, and fruit production. 

Reactivity with formaldehyde: The amino and carbonyl groups in urea react with formaldehyde to form urea formaldehyde resin, which is used for particleboard, plywood, and laminate flooring as a strong and low-cost adhesive. 

Ammonia release during heating: In the exhaust system of diesel engines, urea decomposes into ammonia (NH3) at high temperatures. This ammonia forms harmless nitrogen and water with harmful nitrogen oxides (NOx), making urea the key component of the emission control DEF (AdBlue) ®.

Water solubility: Urea is easily soluble in water and is suitable for liquid fertilizers, skincare products (used as moisturizers), and laboratory solutions (used for protein denaturation).  

conclusion

Urea is a compound composed of carbon, hydrogen, nitrogen, and oxygen, with the chemical formula (NH₂)₂CO. Its simple structure – two amino groups connected to a carbonyl group – gives it unique properties: high nitrogen content, solubility, and reactivity. Whether naturally produced in the liver or synthesized from ammonia and carbon monoxide, the composition of urea makes it indispensable in agriculture, industry, and daily necessities.

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